Our research is focused on modeling, analysis, simulation and software, applied to multiscale, networked systems in biology, materials and social networks. My group has been developing advanced algorithms for discrete stochastic simulation of systems where the fate of a few key molecules can make a big difference to important outcomes. We engage with experimentalists through the analysis of data and the development of mathematical models that yield insight and offer new directions for research. Current collaborations range from biology (circadian rhythm [jet lag] and cell polarization), to medicine (coagulopathy and post-traumatic stress disorder), to ecology (chytrid disease in frogs), to social networks (sentiment analysis and opinion dynamics), to materials. We are collaborating with Prof. Chandra Krintz on the development of an integrated, cloud-based environment called Stochastic Simulation Service (StochSS) for modeling and simulation of biological processes.
Announcements & News
|1.5017840.pdf||Bales, B., Petzold, L., Goodlet, B. R., Lenthe, W. C., & Pollock, T. M. (2018). Bayesian Inference of Elastic Properties with Resonant Ultrasound Spectroscopy. J. Acoust. Soc. Am., 143, pp. 71-83|
|10.10072fs10439-018-2031-9.pdf||Wu, T. B., Wu, S., Buoni, M., Orfeo, T., Brummel-Ziedins, K., Cohen, M., & Petzold, L. (2018). Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy. Ann. Biomed. Eng. pp. 1-10|
|mitchell_et_al-2018-scientific_reports.pdf||Mitchell, B. A. & Petzold, L. R. (2018). Control of Neural Systems at Multiple Scales Using Model-free, Deep Reinforcement Learning. Scientific Reports 8:10721|
|10.1007-s11661-018-4575-6.pdf||Goodlet, B. R., Mills, L., Bales, B., Charpagne, M-A, Murray, S. P., Lenthe, W. C., Petzold, L., & Pollock, T.M. (2018). Elastic Properties of Novel Co- and CoNi-Based Superalloys Determined through Bayesian Inference and Resonant Ultrasound Spectroscopy. Metall. and Mat. Trans. A|
|stancon_alzheimers.pdf||Pourzanjani, A. A., Bales, B. B., Harrington, M., & Petzold, L. R. (2018). Flexible Modeling of Alzheimer's Disease Progression with I-Splines. StanCon 2018 Proceedings.|